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AOD-9604

AOD-9604 5 mg – modified fragment 177-191 of GH

Peptology Ltd. · Peptides for energy and regeneration

AOD-9604 is a modified fragment 177-191 of GH that Peptology supplies strictly for laboratory research, in 5 mg. You can buy AOD-9604 in Cyprus online from €40.00, with same-day dispatch for orders placed by 15:00. 99%+ purity, HPLC/MS certificate for every batch, so every vial comes with documented quality data. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker. The product is not intended for human or veterinary use.

40,00 € · In stock

For research use only / Not a medicine

AOD-9604 5 mg – modified fragment 177-191 of GHAOD-9604 5 mg – modified fragment 177-191 of GH – image 2AOD-9604 5 mg – HPLC purity certificate, batch 0226
Purity>99%
MethodHPLC + LC/MS
LaboratoryAnaliza Białek
Batch0226

Last updated: 18/10/2026

What is AOD-9604?

AOD-9604 (Anti-Obesity Drug 9604) is a modified, stabilised version of growth hormone fragment 176-191. It derives from the lipolytic C-terminal portion of HGH (amino acids 176-191) with the addition of a tyrosine at the N-terminus, which improves the stability of the molecule.

Like the “basic” HGH Frag 176-191, AOD-9604 isolates the lipolytic (fat-burning) action of growth hormone — without activating IGF-1, without an effect on growth and with minimal effect on glucose/insulin levels. It was developed specifically as a research molecule against obesity.

It is studied in research for lipolysis, reduction of body fat and lipid metabolism. Compared with full growth hormone or with IGF-1 analogues such as IGF-1 LR3, AOD-9604 focuses exclusively on the lipolytic arm. See the range in the all peptides category.

In the Peptology version, it is supplied as a lyophilised research-grade powder with purity > 99%, in a 5 mg form. It is intended exclusively for scientific, research and in vitro applications — it is not a medicine and is prohibited in sport (WADA).

Available form: 5 mg

5 MG

Typical research form

High-purity lyophilised powder with a laboratory certificate for each batch.

STRUCTURE

176-191 + Tyr

The lipolytic portion of HGH with tyrosine for stability.

How AOD-9604 works — targeted lipolysis

LIPOLYSIS

Stimulates the breakdown of stored lipids (lipolysis) in fat cells — the main studied effect.

LIPOGENESIS INHIBITION

It is also studied for inhibition of the formation of new fat (lipogenesis), enhancing the overall effect on body composition.

NO IGF-1 / GLUCOSE

It does not activate IGF-1 or significantly affect glucose/insulin — its key characteristic.

How it differs from the “plain” HGH Frag 176-191

AOD-9604 is essentially the stabilised version of HGH Frag 176-191: the addition of tyrosine improves its stability. They share the same rationale — isolating the lipolytic action of GH without an increase in IGF-1 or an effect on glucose — with AOD-9604 having been developed specifically as a research molecule against obesity.

This is how it differs substantially from full growth hormone (which carries the whole range of actions) and from IGF-1 analogues. The mechanisms come from preclinical studies.

Properties and pharmacology

  • Structure: modified GH fragment 176-191 (with tyrosine at the N-terminus)
  • Main action: lipolysis — the “lipolytic” part of growth hormone
  • In addition: studied inhibition of lipogenesis
  • Distinct feature: no IGF-1 activation, no meaningful effect on glucose
  • Relationship: stabilised version of HGH Frag 176-191; anti-obesity research molecule
  • Status: research peptide; prohibited in sport (WADA)

AOD-9604 vs. HGH Frag 176-191 vs. IGF-1 LR3

Comparison of three molecules of the GH/IGF-1 axis with a different focus. Reference data.

AOD-9604 HGH Frag IGF-1 LR3
What it is Stabilised GH fragment GH fragment (176-191) IGF-1 analogue
Main focus Lipolysis Lipolysis Anabolic / regeneration
IGF-1 activation No No Yes (IGF itself)
Stability Improved (tyrosine) Basic Prolonged
Status Research (WADA-prohibited) Research (WADA-prohibited) Research (WADA-prohibited)

Sources: literature on AOD-9604, the GH 176-191 fragment and IGF-1 analogues.

Research

Lipolysis and body composition

AOD-9604 was developed as a research molecule against obesity: in preclinical studies it reproduces the lipolytic action of growth hormone, promoting fat breakdown and studied inhibition of lipogenesis.

Separation of GH actions

The central point of the research is that the molecule does not activate IGF-1 or significantly affect glucose — something that differentiates it from the use of full growth hormone and makes it “focused” on lipolysis.

Data limitations

Clinical data in humans are limited and the results are not always consistent. AOD-9604 remains a research molecule, not approved, and prohibited by WADA.

Note: Scientific reference based on preclinical data. It is not medical advice or a claim for the product.

In brief — scientific profile

176-191
stabilised GH fragment
Lipolysis
main action
↛ IGF-1
no activation
5 mg
available form
Stabilised GH fragment Lipolytic profile Body composition No IGF-1 Anti-obesity 5 mg WADA-banned
  • Stabilised GH fragment 176-191 — with tyrosine for improved stability
  • Targeted lipolysis — fat breakdown + inhibition of lipogenesis (preclinical)
  • No IGF-1 activation — “isolates” fat burning
  • Minimal effect on glucose — unlike full GH
  • Anti-obesity research molecule — stabilised version of HGH Frag
  • Research product — prohibited in sport (WADA)

Side effects and safety

Because of its “focused” profile (no IGF-1 activation or the full actions of GH), AOD-9604 is generally considered well tolerated in the available data. The reactions reported are mostly mild.

Common

  • Injection-site reactions/redness
  • Transient headache
  • Mild fatigue

Less common

  • Dizziness
  • Transient nausea
  • Itching at the site

Precautions

  • Allergic reaction / hypersensitivity
  • Limited data in humans
  • Prohibited in sport (WADA)

Despite the focused profile, any use must remain within the research context. Scientific reference, not an instruction for use.

Related peptides

HGH Frag 176-191

The basic lipolytic fragment

IGF-1 LR3

Anabolic IGF-1 analogue

NAD+ 1000 mg

Energy and metabolism

Peptide Matrix Water™

Recommended reconstitution solvent

See: All peptides · Blog

Laboratory tested
Discreet packaging
Purity certificate
Research product

Research warning: AOD-9604 is offered exclusively for scientific, research and in vitro purposes. It is not intended for human/veterinary use, or for the diagnosis, treatment or prevention of any condition, and does not constitute medical advice. AOD-9604 is prohibited in sport (WADA).

How does it differ from HGH Frag 176-191?

It is its stabilised version. HGH Frag 176-191 is the basic fragment; AOD-9604 adds a tyrosine that improves stability. They share the same lipolytic rationale.

Does AOD-9604 raise IGF-1 like HGH?

No. In published studies in humans , IGF-1 does not increase after AOD-9604.

Molecule identity

CAS number221231-10-3
Molecular weight1815.1 g/mol
Molecular formulaC78H123N23O23S2
ClassModified HGH fragment (177-191)
FormLyophilised powder in a glass vial
StorageLyophilisate: 2–8 °C, dry and protected from light · after reconstitution: 2–8 °C

Buy AOD-9604 in Cyprus – price

You can buy AOD-9604 in Cyprus online from Peptology. Prices by strength:

  • AOD-9604: €40.00

Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.

AOD-9604 5 mg: which strength

AOD-9604 is available in: 5 mg.

Research protocols

Important: Reference information for research purposes — not a recommendation for use or medical advice.

In the research literature, AOD-9604 schedules take the lipolytic character into account:

  • It is often studied administered away from meals (low insulin) for optimal lipolysis
  • Evening or pre-exercise timing is investigated in some protocols
  • Body composition markers are used for monitoring

It is often studied alongside HGH Frag 176-191. The schedules come from the literature and do not constitute a recommendation for individual use.

Storage and reconstitution

Supplied as a lyophilised powder in a 5 mg vial. Lyophilised, it is stable at room temperature, away from light/moisture. For reconstitution, the recommended solvent is Peptide Matrix Water™, which significantly extends the life of the solution.

  • Before reconstitution: room temperature, away from light/moisture; up to 24 months.
  • With Peptide Matrix Water™ (recommended): refrigerator 2–8 °C up to 60 days — the best stability option.
  • With bacteriostatic water or sterile water: refrigerator 2–8 °C up to 28 days. No re-freezing.
  • Reconstitution: add the solvent slowly down the wall, without vigorous agitation.

Laboratory tip: Add Peptide Matrix Water™ to your basket — the recommended stabilising solvent for all reconstituted peptides.

Laboratory protocol — reconstitution, research protocols, storage

Standard protocol, applicable to all research peptides in the Peptology catalogue. For the concentration of the solution (mg/mL) per vial, use the peptide reconstitution calculator.

The 60-second protocol

2. RECONSTITUTION

The solvent is added to the wall of the vial, without agitation, then wait 10–15 minutes.

3. CALCULATION

Calculator → concentration in mg/mL

4. STORAGE

+2 °C to +8 °C, up to 60 days with Peptide Matrix Water

Quick reference

Parameter Value
Form Lyophilised powder
Solvent Peptide Matrix Water
Volume for reconstitution 1–3 mL — 3 mL maximum (capacity of the standard vial)
Storage before reconstitution Room temperature, protected from direct light (refrigeration is not mandatory)
After reconstitution Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water

What you will need

Precision pipette

Calibrated, 100–1000 µL — for accurate measurement of the volume of solvent added to the vial.

70% alcohol pads

Two pads — to disinfect the peptide vial and the solvent vial.

Peptide Matrix Water

Stabilised solvent for lyophilised peptides. Why this one.

Five rules for reconstitution

✅ Correct ❌ Wrong
Disinfect the stoppers and the work surface with 70% alcohol, work with gloves Working without disinfection
The solvent is added slowly down the wall of the vial Direct jet onto the powder — foaming and denaturation
Light swirling between the palms Shaking — foam, on which the peptides denature
Wait 10–15 minutes at room temperature Mechanical mixing or heating
Visual inspection: clear, without particles Using a cloudy or coloured solution

Calculating the concentration

⚠️ Maximum 3 mL of solvent. The standard vial does not allow a larger volume — do not exceed it during reconstitution.

  • Concentration (mg/mL) = mg in the vial ÷ mL of solvent
  • Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
  • 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL

Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after addition (1 mg/mL = 1 µg/µL):

Vial+ 1 mL+ 2 mL+ 3 mL
5 mg5 mg/mL2.5 mg/mL1.67 mg/mL

👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).

Storage

BEFORE RECONSTITUTION

Room temperature, protected from direct light, in the original packaging. Refrigeration is not mandatory.

AFTER RECONSTITUTION

+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard the remainder after this period.

FREEZING

Not recommended. Freeze/thaw cycles degrade the structure of the peptide.

Four mistakes to avoid

1. Shaking for “faster dissolution”

Foam = denaturation. Only gentle swirling between the palms.

2. Unsuitable solvent

For the stability of the peptide structure, use only a sterile, purpose-designed solvent — Peptide Matrix Water is recommended.

3. Ignoring slight cloudiness

If it is not completely clear = the sample does not meet the criteria for work.

4. Removing it from the refrigerator “for an hour or two”

Short exposures add up and jeopardise stability.

Research status: All Peptology products are intended exclusively for laboratory use and research. They are not pharmaceutical products, have not been approved for human or veterinary use and do not replace medical advice. The protocol described is standard laboratory practice for working with lyophilised peptides.

How is it stored?

The lyophilised vial is stored at room temperature, away from light. After reconstitution: with Peptide Matrix Water™ — up to 60 days at 2–8 °C; with bacteriostatic water — up to 28 days.

Purity and certificate of analysis

99%+ purity, HPLC/MS certificate for every batch.

AOD-9604 - 5 mg - Batch - 0226 - Purity

AOD-9604 5 mg – HPLC purity certificate, batch 0226

Shipping and payment

Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.

🚚 Delivery information

  • Orders placed by 15:00 are dispatched the same day, delivery in 5–7 working days.
  • Shipping with BOX NOW, chosen at checkout. Free shipping from €50, otherwise €2.

Frequently asked questions about AOD-9604

Where can I buy AOD-9604 in Cyprus and what does it cost?

In Cyprus you can buy AOD-9604 online from Peptology, from €40.00. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.

What is AOD-9604?

It is a modified, stabilised version of growth hormone fragment 176-191 (with an added tyrosine). It is studied for fat burning without IGF-1 activation or an effect on glucose — it was developed as an anti-obesity research molecule.

In what form is AOD-9604 available?

As a lyophilised powder in a glass vial (5 mg). It is reconstituted in the laboratory with Peptide Matrix Water™ or bacteriostatic water; you can work out the concentration (mg/mL) with the <a href="/page/peptide-calculator">reconstitution calculator</a>.

Which side effects have been reported in clinical studies of AOD-9604?

No worsening was observed in the OGTT in humans (unlike rhGH).

How long does delivery take and how do I pay?

Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.