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HGH Frag
HGH Frag 176-191 5 mg – fragment 176-191 of growth hormone
Peptology Ltd. · Peptides for energy and regeneration
HGH Frag 176-191 is a fragment 176-191 of growth hormone that Peptology supplies strictly for laboratory research, in 5 mg. You can buy HGH Frag 176-191 in Cyprus online from €40.00, with same-day dispatch for orders placed by 15:00. 99%+ purity, HPLC/MS certificate for every batch, so every vial comes with documented quality data. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker. The product is not intended for human or veterinary use.
40,00 € · In stock
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
Last updated: 23/07/2026
What is HGH Frag 176-191?
HGH Frag 176-191 (growth hormone fragment 176-191, HGH Fragment, AOD-9604-related) is a synthetic fragment of the C-terminal end of human growth hormone — corresponding to amino acids 176 to 191. It is exactly the part of GH responsible for the lipolytic (fat-burning) action of the molecule.
Its distinctive characteristic is that it isolates the fat-burning effect of growth hormone, without its other actions — that is, without a substantial rise in IGF-1, without an effect on growth and with minimal effect on glucose/insulin levels.
It is studied in research for lipolysis, reduction of body fat and lipid metabolism. Compared with full Somatropin (which carries the full range of GH actions), it focuses exclusively on the lipolytic arm. See the range in the category all peptides.
In the Peptology version, it is supplied as a lyophilised research-grade powder with purity > 99%, in a 5 mg form. It is intended exclusively for scientific, research and in vitro applications — it is not a medicine and is prohibited in sport (WADA).
Available form: 5 mg
5 MG
Typical research form
High-purity lyophilised powder with a laboratory certificate for each batch.
SEQUENCE
aa 176-191
The lipolytic C-terminal portion of growth hormone.
How HGH Frag acts — targeted lipolysis
LIPOLYSIS
Stimulates the breakdown of stored lipids (lipolysis) in fat cells — the main studied effect.
LIPOGENESIS INHIBITION
It is also studied for inhibition of the formation of new fat (lipogenesis), enhancing the overall effect on body composition.
NO IGF-1 / GLUCOSE
Unlike full GH, it does not substantially raise IGF-1 or significantly affect glucose/insulin.
“Fat burning” without the other actions of GH
The basic rationale behind HGH Frag 176-191 is the separation of the properties of growth hormone: the 176-191 segment retains the lipolytic action, while “leaving behind” the anabolic/growth and diabetogenic (glucose-related) actions of the full molecule.
This is how it essentially differs both from full Somatropin and from Tesamorelin (which reduces visceral fat by raising natural GH/IGF-1). The mechanisms come from preclinical studies.
Properties and pharmacology
- Structure: synthetic fragment of GH (amino acids 176-191, C-terminal end)
- Main action: lipolysis — the “lipolytic” part of growth hormone
- In addition: studied inhibition of lipogenesis
- Difference from full GH: no substantial rise in IGF-1 or effect on glucose
- Focus: body composition / lipid metabolism
- Status: research peptide; prohibited in sport (WADA)
HGH Frag 176-191 vs. Somatropin vs. Tesamorelin
Comparison of three approaches to the GH axis with a different focus on fat. Reference data.
| HGH Frag | Somatropin | Tesamorelin | |
|---|---|---|---|
| What it is | GH fragment (176-191) | Full GH | GHRH analogue |
| Main focus | Lipolysis (general) | Full range of GH | Visceral fat |
| Effect on IGF-1 | Minimal | High | Increases |
| Effect on glucose | Minimal | Significant | Possible |
| Status | Research (WADA-prohibited) | Research (WADA-prohibited) | Research (WADA-prohibited) |
Sources: literature on the GH 176-191 fragment and the molecules of the growth hormone axis.
Research
Lipolysis and body composition
Preclinical studies have shown that the 176-191 fragment reproduces the lipolytic action of growth hormone, promoting fat breakdown and studied inhibition of lipogenesis, without the anabolic actions of the full molecule.
Separation of GH actions
The research interest focuses on the fact that the fragment appears not to significantly affect IGF-1 or glucose — a feature that differentiates it from the use of full growth hormone.
Data limitations
Clinical data in humans are limited and the results are not always consistent. HGH Frag remains a research molecule, not approved, and prohibited by WADA.
Note: Scientific reference based on preclinical data. It is not medical advice or a claim for the product.
In brief — scientific profile
- Synthetic fragment of GH (176-191) — the lipolytic C-terminal part
- Targeted lipolysis — fat breakdown + inhibition of lipogenesis (preclinical)
- No substantial rise in IGF-1 — “isolates” fat burning
- Minimal effect on glucose — unlike full GH
- 5 mg form — lyophilised powder of purity > 99%
- Research product — prohibited in sport (WADA)
Side effects and safety
Because of its “focused” profile (without the full actions of GH), HGH Frag is generally considered well tolerated in the available data. The reactions reported are mostly mild.
Common
- Injection-site reactions/redness
- Transient headache
- Mild fatigue
Less common
- Dizziness
- Transient nausea
- Itching at the site
Precautions
- Allergic reaction / hypersensitivity
- Limited data in humans
- Prohibited in sport (WADA)
Despite the focused profile, any use must remain within the research context. Scientific reference, not an instruction for use.
Related peptides
Somatropin (HGH)
Full growth hormone
Tesamorelin
GHRH analogue for visceral fat
CJC-1295 without DAC
GHRH analogue
Peptide Matrix Water™
Recommended reconstitution solvent
See: All peptides · Blog
Research warning: HGH Frag 176-191 is offered exclusively for scientific, research and in vitro purposes. It is not intended for human/veterinary use, diagnosis, treatment or prevention of any condition and is not medical advice. The growth hormone fragment is prohibited in sport (WADA).
How does it differ from full GH?
Full Somatropin has the full range of actions (growth, IGF-1, glucose, lipolysis). The 176-191 fragment mainly retains lipolysis, without a substantial rise in IGF-1 or significant effect on glucose.
Is this the same as AOD-9604?
Yes — AOD-9604 is the clinical name of the C-terminal fragment 176-191 (variant) that was studied for lipolytic action and safety without activation of IGF-1.
Buy HGH Frag 176-191 in Cyprus – price
You can buy HGH Frag 176-191 in Cyprus online from Peptology. Prices by strength:
- HGH Frag 176-191: €40.00
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
HGH Frag 176-191 5 mg: which strength
HGH Frag 176-191 is available in: 5 mg.
Research protocols
Important: Reference information for research purposes — not a recommendation for use or medical advice.
In the research literature, HGH Frag regimens take into account its lipolytic character and short duration of action:
- It is often studied administered away from meals (low insulin) for optimal lipolysis
- Evening or pre-exercise timing is investigated in some protocols
- Body composition markers are used for monitoring
The regimens come from the literature and are not a recommendation for individual use.
Storage and reconstitution
Supplied as a lyophilised powder in a 5 mg vial. Lyophilised, it is stable at room temperature, away from light/moisture. For reconstitution, the recommended solvent is Peptide Matrix Water™, which significantly extends the life of the solution.
- Before reconstitution: room temperature, away from light/moisture; up to 24 months.
- With Peptide Matrix Water™ (recommended): refrigerator 2–8 °C up to 60 days — the best stability option.
- With bacteriostatic water or sterile water: refrigerator 2–8 °C up to 28 days. No re-freezing.
- Reconstitution: add the solvent slowly down the wall, without vigorous agitation.
Laboratory tip: Add Peptide Matrix Water™ to your basket — the recommended stabilising solvent for all reconstituted peptides.
Laboratory protocol — reconstitution, research protocols, storage
Standard protocol, applicable to all research peptides in the Peptology catalogue. For the concentration of the solution (mg/mL) per vial, use the peptide reconstitution calculator.
The 60-second protocol
1. SOLVENT
2. RECONSTITUTION
The solvent is added to the wall of the vial, without agitation, then wait 10–15 minutes.
3. CALCULATION
Calculator → concentration in mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilised powder |
| Solvent | Peptide Matrix Water |
| Volume for reconstitution | 1–3 mL — 3 mL maximum (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration is not mandatory) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you will need
Precision pipette
Calibrated, 100–1000 µL — for accurate measurement of the volume of solvent added to the vial.
70% alcohol pads
Two pads — to disinfect the peptide vial and the solvent vial.
Stabilised solvent for lyophilised peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Wrong |
|---|---|
| Disinfect the stoppers and the work surface with 70% alcohol, work with gloves | Working without disinfection |
| The solvent is added slowly down the wall of the vial | Direct jet onto the powder — foaming and denaturation |
| Light swirling between the palms | Shaking — foam, on which the peptides denature |
| Wait 10–15 minutes at room temperature | Mechanical mixing or heating |
| Visual inspection: clear, without particles | Using a cloudy or coloured solution |
Calculating the concentration
⚠️ Maximum 3 mL of solvent. The standard vial does not allow a larger volume — do not exceed it during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after addition (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 5 mg | 5 mg/mL | 2.5 mg/mL | 1.67 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in the original packaging. Refrigeration is not mandatory.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard the remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade the structure of the peptide.
Four mistakes to avoid
1. Shaking for “faster dissolution”
Foam = denaturation. Only gentle swirling between the palms.
2. Unsuitable solvent
For the stability of the peptide structure, use only a sterile, purpose-designed solvent — Peptide Matrix Water is recommended.
3. Ignoring slight cloudiness
If it is not completely clear = the sample does not meet the criteria for work.
4. Removing it from the refrigerator “for an hour or two”
Short exposures add up and jeopardise stability.
Research status: All Peptology products are intended exclusively for laboratory use and research. They are not pharmaceutical products, have not been approved for human or veterinary use and do not replace medical advice. The protocol described is standard laboratory practice for working with lyophilised peptides.
How is it stored?
The lyophilised vial is stored at room temperature, away from light. After reconstitution: with Peptide Matrix Water™ — up to 60 days at 2–8 °C; with bacteriostatic water — up to 28 days.
Purity and certificate of analysis
99%+ purity, HPLC/MS certificate for every batch.
HGH Frag - 5 mg - Batch - 0226 - Purity
Shipping and payment
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
🚚 Delivery information
- Orders placed by 15:00 are dispatched the same day, delivery in 5–7 working days.
-
Shipping with BOX NOW, chosen at checkout. Free shipping from €50, otherwise €2.
Frequently asked questions about HGH Frag 176-191
Where can I buy HGH Frag 176-191 in Cyprus and what does it cost?
In Cyprus you can buy HGH Frag 176-191 online from Peptology, from €40.00. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
What is HGH Frag 176-191?
It is a synthetic fragment of growth hormone (amino acids 176-191) — exactly the part responsible for its lipolytic action. It is studied for fat burning without the other actions of full GH.
In what form is HGH Frag 176-191 available?
As a lyophilised powder in a glass vial (5 mg). It is reconstituted in the laboratory with Peptide Matrix Water™ or bacteriostatic water; you can work out the concentration (mg/mL) with the <a href="/page/peptide-calculator">reconstitution calculator</a>.
Which side effects have been reported in clinical studies of HGH Frag 176-191?
Because of its “focused” profile (without the full actions of GH), HGH Frag is generally considered well tolerated in the available data. The reactions reported are mostly mild.
How long does delivery take and how do I pay?
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.