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Vilon
Vilon 20 mg – synthetic dipeptide Lys-Glu
Peptology Ltd. · Peptides for immunity and hormonal balance
Vilon is a synthetic dipeptide Lys-Glu that Peptology supplies strictly for laboratory research, in 20 mg. You can buy Vilon in Cyprus online from €40.00, with same-day dispatch for orders placed by 15:00. 99%+ purity, HPLC/MS certificate for every batch, so every vial comes with documented quality data. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker. The product is not intended for human or veterinary use.
40,00 € · In stock
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
Last updated: 18/10/2026
What is Vilon?
Vilon is a synthetic Lys-Glu dipeptide (lysine-glutamic acid, also known as KE), one of the short peptide bioregulators of the Khavinson school (Institute of Bioregulation and Gerontology, St Petersburg). It is cited as one of the shortest peptides with documented biological activity — only two amino acids.
Bioregulators are a class of short peptides studied for tissue-specific regulation of gene expression. Vilon is the thymic/immune representative of this family and is studied mainly for regulation of immune function and in the context of longevity. The same group includes Epithalon (a telomeric/pineal bioregulator) and thymic peptides such as Thymulin.
At Peptology it is supplied as a lyophilised research peptide with purity above 99% (see certificates), with a price in Cyprus and pay on delivery. Exclusively for research purposes; it is not a medicine. See also the related bioregulators Epithalon and Thymulin.
How Vilon is studied — mechanism
In the Khavinson school literature, Vilon is described as a bioregulator acting at the level of gene expression in immune cells. The three axes below summarise the main directions of study of the dipeptide.
IMMUNE REGULATION
Studied as a thymic/immune bioregulator, linked to the function and maturation of T lymphocytes.
GENE EXPRESSION
Regulation of gene expression through “chromatin decondensation” is described — activation of “silent” genes in aged cells.
GERONTOLOGY
Examined in the context of bioregulation and restoration of functions during ageing.
The concept of peptide bioregulation
The hypothesis of the Khavinson school is that very short peptides can enter the cell and the nucleus and bind to specific regions of DNA, influencing which genes are active. During ageing some genes become “silent” through chromatin condensation; according to this concept, bioregulators such as Vilon can “open” such regions and restore their expression — a mechanism studied mainly in immune and thymic cells.
Why the thymus
The thymus is the organ where T lymphocytes mature, and it shrinks progressively with age (atrophy), which is linked to a weakening of the immune response. Vilon is studied precisely as a thymic bioregulator — in the context of maintaining immune function during ageing.
Khavinson's bioregulators
The family of short peptide bioregulators was developed in St Petersburg and includes tissue-specific peptides, each directed at a specific organ or system. Below is Vilon's place among them.
VILON (KE)
Thymic/immune bioregulator — Lys-Glu dipeptide.
EPITHALON
Pineal/telomeric bioregulator — AEDG tetrapeptide.
THYMIC PEPTIDES
Thymulin, Thymosin — immune regulation and neuroimmune regulation.
Properties and characteristics
- Sequence: Lys-Glu (lysine-glutamic acid), known as KE
- Class: short peptide bioregulator (Khavinson school)
- Profile: thymic/immune bioregulator
- Quantity: 20 mg per vial, lyophilised powder
- Purity: above 99%, with a CoA for each batch
- Status: in research protocols it is applied in short cycles
- Application: exclusively for research (in vitro / preclinical models)
Vilon among the bioregulators
The table compares Vilon with other bioregulators by sequence and research direction. Each is tissue-specific and concerns a different system.
| Vilon | Epithalon | Thymulin | |
|---|---|---|---|
| Sequence | Lys-Glu (KE) | Ala-Glu-Asp-Gly | peptide + Zn |
| Research axis | Immunity / thymus | Telomeres / longevity | Neuroimmune regulation |
| Length | 2 amino acids | 4 amino acids | longer |
| Status | Short cycles | Cycles | Cycles |
The comparison is made by composition and direction, for scientific reference. It is not a claim of comparative efficacy.
Scientific basis and availability of data
Research by the Khavinson school
Most of the research on Vilon comes from the group of Prof. Khavinson and collaborators. It describes effects on the maturation and function of T lymphocytes, on immune regulation and on ageing markers in animal and cell models, as well as interactions with components of the NF-κB pathway.
Limitations of the evidence
Since much of the data comes from a single research group, independent replication is limited. This does not diminish the research value of Vilon, but it requires that efficacy data be interpreted with this reservation — and it is the reason it is offered only for research purposes.
The information is a scientific reference and concerns mainly research by the Khavinson group. It is not a claim of results or a recommendation for use.
Documented research focus
- Immune regulation — function and maturation of T lymphocytes in models of immune regulation.
- Thymus function — bioregulation in the context of age-related thymic atrophy.
- Gene expression — “chromatin decondensation” and activation of silent genes in aged cells.
- Longevity — ageing markers in preclinical models.
The directions concern mainly research by the Khavinson group and are not a claim of results or a recommendation for use.
Related products
Epithalon
Telomeric bioregulator (AEDG)
Thymulin
Neuroimmune regulator
Thymosin Alpha-1
Immunostimulatory peptide
Peptide Matrix Water™
Reconstitution solution
See also: Epithalon · Thymulin · Blog
Research warning: Vilon (Lys-Glu) is offered exclusively for research purposes and in vitro applications. It is not approved for clinical use, is not a medicine and is not intended for consumption by humans or animals. The information concerns mainly research by the Khavinson group and is for scientific reference only, not medical advice or a recommendation for use. Peptology bears no responsibility for unauthorised use of research peptides.
What are Khavinson's bioregulators?
A family of short peptides studied for tissue-specific regulation of gene expression and of functions during ageing. Vilon is the thymic/immune representative.
Molecule identity
| CAS number | 45234-02-4 |
|---|---|
| Molecular weight | 275.30 g/mol |
| Molecular formula | C11H21N3O5 |
| Class | Bioregulatory dipeptide (Lys-Glu) |
| Form | Lyophilised powder in a glass vial |
| Storage | Lyophilisate: 2–8 °C, dry and protected from light · after reconstitution: 2–8 °C |
Buy Vilon in Cyprus – price
You can buy Vilon in Cyprus online from Peptology. Prices by strength:
- Vilon: €40.00
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
Vilon 20 mg: which strength
Vilon is available in: 20 mg.
Research protocols
Important: The information below summarises ranges observed among researchers and is not a recommendation for use, medical advice or an application instruction.
- The 20 mg vial is usually reconstituted with ~3 mL of liquid (~6.67 mg/mL).
- In protocols, bioregulators are applied in short cycles (e.g. ~5–10 days) within a longer period.
- The concentration is determined by the reconstitution volume and the aims of the research.
Storage and reconstitution
- Before reconstitution: lyophilised at −20 °C (−80 °C for long-term storage), in the dark and dry.
- After reconstitution: in the refrigerator at 2–8 °C, use within ~a week, or divide into portions and freeze.
- Reconstitution: add the liquid slowly down the wall of the vial; swirl gently, do not shake.
For reconstitution we recommend Peptide Matrix Water™ — a stabilising solution for reconstituted research peptides; alternatively, bacteriostatic water.
Laboratory protocol — reconstitution, research protocols, storage
Standard protocol, applicable to all research peptides in the Peptology catalogue. For the concentration of the solution (mg/mL) per vial, use the peptide reconstitution calculator.
The 60-second protocol
1. SOLVENT
2. RECONSTITUTION
The solvent is added to the wall of the vial, without agitation, then wait 10–15 minutes.
3. CALCULATION
Calculator → concentration in mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilised powder |
| Solvent | Peptide Matrix Water |
| Volume for reconstitution | 1–3 mL — 3 mL maximum (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration is not mandatory) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you will need
Precision pipette
Calibrated, 100–1000 µL — for accurate measurement of the volume of solvent added to the vial.
70% alcohol pads
Two pads — to disinfect the peptide vial and the solvent vial.
Stabilised solvent for lyophilised peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Wrong |
|---|---|
| Disinfect the stoppers and the work surface with 70% alcohol, work with gloves | Working without disinfection |
| The solvent is added slowly down the wall of the vial | Direct jet onto the powder — foaming and denaturation |
| Light swirling between the palms | Shaking — foam, on which the peptides denature |
| Wait 10–15 minutes at room temperature | Mechanical mixing or heating |
| Visual inspection: clear, without particles | Using a cloudy or coloured solution |
Calculating the concentration
⚠️ Maximum 3 mL of solvent. The standard vial does not allow a larger volume — do not exceed it during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after addition (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 20 mg | 20 mg/mL | 10 mg/mL | 6.67 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in the original packaging. Refrigeration is not mandatory.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard the remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade the structure of the peptide.
Four mistakes to avoid
1. Shaking for “faster dissolution”
Foam = denaturation. Only gentle swirling between the palms.
2. Unsuitable solvent
For the stability of the peptide structure, use only a sterile, purpose-designed solvent — Peptide Matrix Water is recommended.
3. Ignoring slight cloudiness
If it is not completely clear = the sample does not meet the criteria for work.
4. Removing it from the refrigerator “for an hour or two”
Short exposures add up and jeopardise stability.
Research status: All Peptology products are intended exclusively for laboratory use and research. They are not pharmaceutical products, have not been approved for human or veterinary use and do not replace medical advice. The protocol described is standard laboratory practice for working with lyophilised peptides.
Purity and certificate of analysis
99%+ purity, HPLC/MS certificate for every batch.
Vilon - 20 mg - Batch - 0226 - Purity
Shipping and payment
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
🚚 Delivery information
- Orders placed by 15:00 are dispatched the same day, delivery in 5–7 working days.
- Shipping with BOX NOW, chosen at checkout. Free shipping from €50, otherwise €2.
Frequently asked questions about Vilon
Where can I buy Vilon in Cyprus and what does it cost?
In Cyprus you can buy Vilon online from Peptology, from €40.00. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
What is Vilon?
Vilon is the Lys-Glu (KE) dipeptide — one of the shortest peptides with documented biological activity.
In what form is Vilon available?
As a lyophilised powder in a glass vial (20 mg). It is reconstituted in the laboratory with Peptide Matrix Water™ or bacteriostatic water; you can work out the concentration (mg/mL) with the <a href="/page/peptide-calculator">reconstitution calculator</a>.
Which side effects have been reported in clinical studies of Vilon?
Peptology does not publish its own safety data for Vilon; for adverse events, see the original publications of clinical and preclinical studies. The product is supplied strictly for laboratory research and is not intended for human or veterinary use.
How long does delivery take and how do I pay?
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.