🇨🇾 BOX NOW delivery in 5–7 working days ✅ Pay on delivery 📦 Free shipping from €50
Thymosin Alpha-1
Thymosin Alpha-1 5/10 mg – 28-amino-acid thymic peptide
Peptology Ltd. · Peptides for immunity and hormonal balance
Thymosin Alpha-1 is a 28-amino-acid thymic peptide that Peptology supplies strictly for laboratory research, in 5/10 mg. You can buy Thymosin Alpha-1 in Cyprus online from €30.00, with same-day dispatch for orders placed by 15:00. 99%+ purity, HPLC/MS certificate for every batch, so every vial comes with documented quality data. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker. The product is not intended for human or veterinary use.
30,00 € · In stock
- 5mg — 30,00 €
- 10mg — 45,00 €
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
Last updated: 18/10/2026
What is Thymosin Alpha-1?
Thymosin Alpha-1 (Tα1, Talpha1) is a thymic peptide of 28 amino acids produced naturally by the thymus gland. It is one of the most studied immune potentiators and is regarded as a central regulator of cell-mediated immunity.
Unlike a simple immunosuppressant or immune enhancer, Thymosin Alpha-1 acts as a regulator: it strengthens the response of T lymphocytes and dendritic cells via signalling through Toll-like receptors (TLRs), improving the body’s ability to recognise and deal with pathogens and abnormal cells.
It is widely studied for enhancing immune function, as an immunological adjuvant, and in some countries it has been studied clinically in viral and immune conditions. See the range in the all peptides category.
In the Peptology version, it is supplied as a lyophilised research-grade powder with purity > 99%, in two formats — 5 mg and 10 mg. It is intended exclusively for scientific, research and in vitro applications — it is not a medicine or a supplement in this form.
Available formats: 5 mg and 10 mg
5 MG
Typical form
For validation experiments and protocols of usual size.
10 MG
Extended form
For longer courses and higher-consumption protocols.
Both forms have purity > 99% and a laboratory certificate for each batch. The choice depends on the scale of the protocol.
How Thymosin Alpha-1 works — regulation of immunity
TLR RECEPTORS
It signals through Toll-like receptors (mainly TLR2/TLR9) on immune cells, activating innate and adaptive immunity pathways.
T & DENDRITIC CELLS
It promotes the maturation of dendritic cells and the differentiation of T lymphocytes, strengthening cell-mediated defence.
CYTOKINE BALANCE
It regulates the balance of cytokines (e.g. towards Th1), strengthening antiviral and anticancer immune surveillance in preclinical models.
A “regulator”, not a simple stimulant
The characteristic of Thymosin Alpha-1 is that it restores or strengthens a weakened immune response without over-activating it needlessly. That is why it is studied as an immunological adjuvant — for example, for enhancing the response to vaccines or in states of immunosuppression.
Compared with Thymulin (which is zinc-dependent and has a strong neuroimmunological component), Thymosin Alpha-1 focuses more on direct strengthening of cell-mediated immunity. The mechanisms come from clinical and preclinical studies.
Properties and pharmacology
- Origin: thymic peptide of 28 amino acids (a fragment of prothymosin alpha)
- Target: Toll-like receptors (TLRs) on immune cells
- Main action: strengthening cell-mediated immunity, maturation of T and dendritic cells
- Profile: immunomodulator/immune stimulant (not an immunosuppressant)
- Clinical background: clinical studies in some countries
- Status here: research peptide, not approved in this form
Thymosin Alpha-1 vs. Thymulin vs. TB-500
Comparison of three peptides with an immunological or regenerative component. Reference data.
| Thymosin Alpha-1 | Thymulin | TB-500 | |
|---|---|---|---|
| Size | 28 amino acids | 9 amino acids | Thymosin Beta-4 fragment |
| Main role | Immune enhancement (cell-mediated) | Immunoregulation + neuro | Tissue repair |
| Mechanism | TLR receptors | Zinc dependence | Actin binding |
| Clinical approval | Yes (some countries) | No (research) | No (research) |
| Status here | Research | Research | Research (WADA-prohibited) |
Sources: clinical studies of Thymosin Alpha-1 and literature on thymic peptides.
Research
Strengthening cell-mediated immunity
Clinical and preclinical studies show that Thymosin Alpha-1 enhances the maturation and function of T lymphocytes and dendritic cells, with documented use as an immunological adjuvant.
Viral and immune conditions
In some countries it has been studied clinically in viral hepatitis and as adjunctive therapy in immunosuppression; it has also been investigated for enhancing the response to vaccines.
Context of the data
Although there is a strong clinical background in approved indications, this particular form is offered as a research product. Any clinical application belongs to the responsibility of healthcare professionals.
Note: Scientific reference based on clinical/preclinical data. It is not medical advice or a claim for the product.
In brief — scientific profile
- Thymic peptide of 28 amino acids — among the most studied immune stimulants
- Signalling via TLR — activation of innate and adaptive immunity
- Strengthens cell-mediated defence — T lymphocytes and dendritic cells
- A regulator, not a simple stimulant — restores weakened immunity
- Two formats — 5 mg and 10 mg for different protocol scales
- Research product — not approved in this form
Side effects and safety
In the clinical data, Thymosin Alpha-1 is generally considered well tolerated. The reactions reported are mostly mild and local.
Common
- Injection-site reactions
- Transient redness / discomfort
- Mild fatigue
Less common
- Transient myalgia / arthralgia
- Headache
- Transient immunological fluctuations
Precautions
- Allergic reaction / hypersensitivity
- Caution in autoimmune conditions
- Caution with transplant immunosuppression
Because it strengthens the immune response, there is a theoretical precaution in autoimmune conditions or planned immunosuppression. Scientific reference, not instructions for use.
Related peptides
Thymulin
Neuroimmunoregulatory thymic peptide
TB-500
Thymosin Beta-4 fragment — repair
Epithalon
Ageing bioregulator peptide
Peptide Matrix Water™
Recommended reconstitution solvent
See: All peptides · Blog
Research warning: Thymosin Alpha-1 is offered exclusively for scientific, research and in vitro purposes. It is not intended for human/veterinary use, or for the diagnosis, treatment or prevention of any condition, and does not constitute medical advice.
How does it differ from Thymulin?
Both are thymic peptides. Thymosin Alpha-1 (28 amino acids) focuses on strengthening cell-mediated immunity via TLR; Thymulin (9 amino acids) is zinc-dependent and has a strong neuroimmunological/anti-inflammatory action.
Molecule identity
| CAS number | 62304-98-7 |
|---|---|
| Molecular weight | 3108.3 g/mol |
| Molecular formula | C129H215N33O55 |
| Class | Thymic peptide (28 amino acids) |
| Form | Lyophilised powder in a glass vial |
| Storage | Lyophilisate: 2–8 °C, dry and protected from light · after reconstitution: 2–8 °C |
Buy Thymosin Alpha-1 in Cyprus – price
You can buy Thymosin Alpha-1 in Cyprus online from Peptology. Prices by strength:
- 5mg: €30.00
- 10mg: €45.00
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
Thymosin Alpha-1 5/10 mg: which strength
Thymosin Alpha-1 is available in: 5/10 mg.
Research protocols
Important: Reference information for research purposes — not a recommendation for use or medical advice.
In the clinical and research literature, Thymosin Alpha-1 schedules are shaped around its immunoregulatory character:
- It is often studied in repeated administrations per week, in cycles
- In an adjuvant role, administration is coordinated with the corresponding stimulus (e.g. a vaccine)
- Immunological markers (e.g. T-cell populations) are used to monitor the response
The schedules come from the clinical/research literature and do not constitute a recommendation for individual use.
Storage and reconstitution
It is supplied as a lyophilised powder in a vial (5 or 10 mg). Lyophilised, it is stable at room temperature, away from light/humidity. For reconstitution, the recommended solvent is Peptide Matrix Water™, which significantly extends the shelf life of the solution.
- Before reconstitution: room temperature, away from light/moisture; up to 24 months.
- With Peptide Matrix Water™ (recommended): refrigerator 2–8 °C up to 60 days — the best stability option.
- With bacteriostatic water or sterile water: refrigerator 2–8 °C up to 28 days. No re-freezing.
- Reconstitution: add the solvent slowly down the wall, without vigorous agitation.
Laboratory tip: Add Peptide Matrix Water™ to your basket — the recommended stabilising solvent for all reconstituted peptides.
Laboratory protocol — reconstitution, research protocols, storage
Standard protocol, applicable to all research peptides in the Peptology catalogue. For the concentration of the solution (mg/mL) per vial, use the peptide reconstitution calculator.
The 60-second protocol
1. SOLVENT
2. RECONSTITUTION
The solvent is added to the wall of the vial, without agitation, then wait 10–15 minutes.
3. CALCULATION
Calculator → concentration in mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilised powder |
| Solvent | Peptide Matrix Water |
| Volume for reconstitution | 1–3 mL — 3 mL maximum (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration is not mandatory) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you will need
Precision pipette
Calibrated, 100–1000 µL — for accurate measurement of the volume of solvent added to the vial.
70% alcohol pads
Two pads — to disinfect the peptide vial and the solvent vial.
Stabilised solvent for lyophilised peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Wrong |
|---|---|
| Disinfect the stoppers and the work surface with 70% alcohol, work with gloves | Working without disinfection |
| The solvent is added slowly down the wall of the vial | Direct jet onto the powder — foaming and denaturation |
| Light swirling between the palms | Shaking — foam, on which the peptides denature |
| Wait 10–15 minutes at room temperature | Mechanical mixing or heating |
| Visual inspection: clear, without particles | Using a cloudy or coloured solution |
Calculating the concentration
⚠️ Maximum 3 mL of solvent. The standard vial does not allow a larger volume — do not exceed it during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after addition (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 5 mg | 5 mg/mL | 2.5 mg/mL | 1.67 mg/mL |
| 10 mg | 10 mg/mL | 5 mg/mL | 3.33 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in the original packaging. Refrigeration is not mandatory.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard the remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade the structure of the peptide.
Four mistakes to avoid
1. Shaking for “faster dissolution”
Foam = denaturation. Only gentle swirling between the palms.
2. Unsuitable solvent
For the stability of the peptide structure, use only a sterile, purpose-designed solvent — Peptide Matrix Water is recommended.
3. Ignoring slight cloudiness
If it is not completely clear = the sample does not meet the criteria for work.
4. Removing it from the refrigerator “for an hour or two”
Short exposures add up and jeopardise stability.
Research status: All Peptology products are intended exclusively for laboratory use and research. They are not pharmaceutical products, have not been approved for human or veterinary use and do not replace medical advice. The protocol described is standard laboratory practice for working with lyophilised peptides.
How is it stored?
The lyophilised vial is stored at room temperature, away from light. After reconstitution: with Peptide Matrix Water™ — up to 60 days at 2–8 °C; with bacteriostatic water — up to 28 days.
Purity and certificate of analysis
99%+ purity, HPLC/MS certificate for every batch.
Thymosin Alpha‑1 - 5mg - Batch - 0226 - Purity
Thymosin Alpha‑1 - 10mg - Batch - 0226 - Purity
Shipping and payment
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
🚚 Delivery information
- Orders placed by 15:00 are dispatched the same day, delivery in 5–7 working days.
-
Shipping with BOX NOW, chosen at checkout. Free shipping from €50, otherwise €2.
Frequently asked questions about Thymosin Alpha-1
Where can I buy Thymosin Alpha-1 in Cyprus and what does it cost?
In Cyprus you can buy Thymosin Alpha-1 online from Peptology, from €30.00 (5mg: €30.00, 10mg: €45.00). Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
What is Thymosin Alpha-1?
It is a thymic peptide of 28 amino acids, among the most studied immune stimulants. It acts through TLR receptors, strengthening T lymphocytes and dendritic cells — improving cell-mediated defence.
In what form is Thymosin Alpha-1 available?
As a lyophilised powder in a glass vial (5/10 mg). It is reconstituted in the laboratory with Peptide Matrix Water™ or bacteriostatic water; you can work out the concentration (mg/mL) with the <a href="/page/peptide-calculator">reconstitution calculator</a>.
Which side effects have been reported in clinical studies of Thymosin Alpha-1?
In the clinical data, Thymosin Alpha-1 is generally considered well tolerated. The reactions reported are mostly mild and local.
How long does delivery take and how do I pay?
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.