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SLU-PP-332
SLU-PP-332 5 mg – synthetic ERRα/β/γ agonist
Peptology Ltd. · Peptides for energy and regeneration
SLU-PP-332 is a synthetic ERRα/β/γ agonist that Peptology supplies strictly for laboratory research, in 5 mg. You can buy SLU-PP-332 in Cyprus online from €75.00, with same-day dispatch for orders placed by 15:00. 99%+ purity, HPLC/MS certificate for every batch, so every vial comes with documented quality data. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker. The product is not intended for human or veterinary use.
75,00 € · Out of stock
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
Last updated: 18/10/2026
What is SLU-PP-332?
SLU-PP-332 is a synthetic small molecule that acts as an agonist (pan-agonist) of the ERR receptors — the Estrogen-Related Receptors ERRα, ERRβ and ERRγ. It is one of the most recent “exercise mimetics” in metabolism and mitochondrial function research.
Note on accuracy: Unlike most products in the catalogue, SLU-PP-332 is not a peptide but a small molecule (a nuclear receptor agonist). It is included here as a metabolic/mitochondrial research tool, alongside molecules such as MOTS-c and AICAR.
ERR receptors are central regulators of oxidative metabolism and mitochondrial function. By activating them, SLU-PP-332 stimulates mitochondrial biogenesis, fatty acid oxidation, energy expenditure and endurance — without actual exercise. See the range in the all products category.
In the Peptology version, it is supplied as a lyophilised research-grade powder with purity > 99%, in a 5 mg format. It is intended exclusively for scientific, research and in vitro applications — it is not a medicine or a supplement.
Available form: 5 mg
5 MG
Typical research form
High-purity lyophilised powder with a laboratory certificate for each batch.
TARGET
ERRα/β/γ
Pan-agonist of all three ERR isoforms.
How SLU-PP-332 works — ERR activation
ERR RECEPTORS
It activates the nuclear receptors ERRα/β/γ — “master regulators” of the expression of oxidative metabolism genes.
MITOCHONDRIAL BIOGENESIS
It promotes the creation of new mitochondria and fatty acid oxidation — key features of adaptation to exercise.
ENERGY EXPENDITURE & ENDURANCE
In preclinical models it increases energy expenditure and endurance, with studied improvement in metabolic health.
An “exercise mimetic” via a different pathway
While other “exercise mimetics” act through AMPK (such as AICAR or the peptide MOTS-c), SLU-PP-332 acts through the ERR receptors — a branch that directly regulates the expression of mitochondrial/oxidative metabolism genes. It thus offers a distinct strategy in the study of metabolic adaptation.
In preclinical studies, ERR activation was linked with increased fat oxidation, improved endurance and energy expenditure — without an increase in food intake. The mechanisms come from preclinical studies and constitute an active, newer field of research.
Properties and pharmacology
- Class: synthetic small molecule — ERR pan-agonist; not a peptide
- Target: nuclear receptors ERRα, ERRβ, ERRγ
- Main action: regulation of oxidative/mitochondrial metabolism genes
- Studied actions: mitochondrial biogenesis, fat oxidation, endurance, energy expenditure
- Characterisation: “exercise mimetic” (via ERR)
- Status: research molecule, not approved; newer field of research
SLU-PP-332 vs. AICAR vs. MOTS-c
Comparison of three “exercise mimetics” with different molecular pathways. Reference data.
| SLU-PP-332 | AICAR | MOTS-c | |
|---|---|---|---|
| Molecule type | Small molecule | Nucleotide analogue | Mitochondrial peptide |
| Mechanism | ERRα/β/γ agonist | AMPK activation | AMPK activation |
| “Exercise mimetic” | Yes (via ERR) | Yes (classic) | Yes |
| Main focus | Mitochondria / endurance | Metabolism / endurance | Metabolic regulation |
| Status | Research | Research (WADA-prohibited) | Research |
Sources: literature on ERR receptors, SLU-PP-332 and “exercise mimetics”.
Research
ERR, mitochondria and endurance
In preclinical studies, SLU-PP-332 activated the ERR receptors and increased mitochondrial biogenesis, fatty acid oxidation and endurance in animal models — reproducing elements of adaptation to exercise.
Energy expenditure and body composition
It was linked with increased energy expenditure and improved metabolic markers, without an increase in food intake — which is why it is studied in the context of metabolic health.
Data limitations
It is a newer molecule with mainly preclinical data; clinical studies in humans are lacking. SLU-PP-332 remains strictly a research molecule, not approved for clinical use.
Note: Scientific reference based on preclinical data. It is not medical advice or a claim for the product.
In brief — scientific profile
- Synthetic small molecule — ERRα/β/γ pan-agonist (not a peptide)
- Regulates oxidative metabolism genes — via nuclear receptors
- Mitochondrial biogenesis & fat oxidation — elements of exercise adaptation
- “Exercise mimetic” via ERR — a pathway distinct from AMPK
- 5 mg form — lyophilised powder of purity > 99%
- Research product — newer, not approved for clinical use
Side effects and safety
As a newer research molecule, the safety profile of SLU-PP-332 in humans has not been characterised; the data come exclusively from preclinical studies. Particular caution is required.
Possible (preclinical)
- Injection-site reactions
- Transient fatigue
- Mild metabolic fluctuations
Unknown
- Long-term safety
- Effects on ERR-expressing tissues (e.g. heart)
- Human bioavailability
Precautions
- Allergic reaction / hypersensitivity
- Very limited data
- Strictly laboratory use only
Because ERR receptors are also expressed in tissues such as the heart, the long-term effects are not known. Scientific reference, not instructions for use.
Related products
AICAR
Exercise mimetic (AMPK)
MOTS-c
Mitochondrial peptide
NAD+ 1000 mg
Energy and metabolism
Peptide Matrix Water™
Recommended reconstitution solvent
See: All products · Blog
Research warning: SLU-PP-332 is offered exclusively for scientific, research and in vitro purposes. It is not intended for human/veterinary use, or for the diagnosis, treatment or prevention of any condition, and does not constitute medical advice. It is a newer molecule with limited safety data.
Is SLU-PP-332 a peptide?
No. It is a synthetic small molecule that acts as an agonist of the nuclear receptors ERRα/β/γ. It is included in the catalogue as a metabolic/mitochondrial research tool, but it is not a peptide.
How does it differ from AICAR?
Both are small-molecule “exercise mimetics”. AICAR acts through AMPK; SLU-PP-332 through the ERR receptors — a distinct metabolic pathway.
Which tissues are most affected?
Skeletal muscle, liver, adipose tissue and kidneys show improvements in mitochondrial and inflammatory markers in rodents.
Molecule identity
| CAS number | 303760-60-3 |
|---|---|
| Molecular weight | 290.3 g/mol |
| Molecular formula | C18H14N2O2 |
| Class | Synthetic ERRα/β/γ agonist (small molecule) |
| Form | Lyophilised powder in a glass vial |
| Storage | Lyophilisate: 2–8 °C, dry and protected from light · after reconstitution: 2–8 °C |
Buy SLU-PP-332 in Cyprus – price
You can buy SLU-PP-332 in Cyprus online from Peptology. Prices by strength:
- SLU-PP-332: €75.00
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
SLU-PP-332 5 mg: which strength
SLU-PP-332 is available in: 5 mg.
Research protocols
Important: Reference information for research purposes — not a recommendation for use or medical advice.
In the research literature, SLU-PP-332 schedules are shaped around its metabolic/mitochondrial character:
- In preclinical models it is studied in cycles, with markers of mitochondrial function/endurance
- Timing relative to activity is investigated in some protocols
- As a newer molecule, bioavailability and optimal schedules are an active field of research
It is sometimes studied together with other metabolic molecules such as MOTS-c or AICAR. The schedules come from the literature and do not constitute a recommendation for individual use.
Storage and reconstitution
It is supplied as a lyophilised powder in a 5 mg vial. As a small molecule it is relatively stable at room temperature, away from light/humidity. For reconstitution, the recommended solvent is Peptide Matrix Water™, which extends the shelf life of the solution.
- Before reconstitution: room temperature, away from light/moisture; up to 24 months.
- With Peptide Matrix Water™ (recommended): refrigerator 2–8 °C up to 60 days — the best stability option.
- With bacteriostatic water or sterile water: refrigerator 2–8 °C up to 28 days. No re-freezing.
- Reconstitution: add the solvent slowly down the wall, without vigorous agitation.
Laboratory tip: Add Peptide Matrix Water™ to your basket — the recommended stabilising solvent for all reconstituted products.
Laboratory protocol — reconstitution, research protocols, storage
Standard protocol, applicable to all research peptides in the Peptology catalogue. For the concentration of the solution (mg/mL) per vial, use the peptide reconstitution calculator.
The 60-second protocol
1. SOLVENT
2. RECONSTITUTION
The solvent is added to the wall of the vial, without agitation, then wait 10–15 minutes.
3. CALCULATION
Calculator → concentration in mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilised powder |
| Solvent | Peptide Matrix Water |
| Volume for reconstitution | 1–3 mL — 3 mL maximum (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration is not mandatory) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you will need
Precision pipette
Calibrated, 100–1000 µL — for accurate measurement of the volume of solvent added to the vial.
70% alcohol pads
Two pads — to disinfect the peptide vial and the solvent vial.
Stabilised solvent for lyophilised peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Wrong |
|---|---|
| Disinfect the stoppers and the work surface with 70% alcohol, work with gloves | Working without disinfection |
| The solvent is added slowly down the wall of the vial | Direct jet onto the powder — foaming and denaturation |
| Light swirling between the palms | Shaking — foam, on which the peptides denature |
| Wait 10–15 minutes at room temperature | Mechanical mixing or heating |
| Visual inspection: clear, without particles | Using a cloudy or coloured solution |
Calculating the concentration
⚠️ Maximum 3 mL of solvent. The standard vial does not allow a larger volume — do not exceed it during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after addition (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 5 mg | 5 mg/mL | 2.5 mg/mL | 1.67 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in the original packaging. Refrigeration is not mandatory.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard the remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade the structure of the peptide.
Four mistakes to avoid
1. Shaking for “faster dissolution”
Foam = denaturation. Only gentle swirling between the palms.
2. Unsuitable solvent
For the stability of the peptide structure, use only a sterile, purpose-designed solvent — Peptide Matrix Water is recommended.
3. Ignoring slight cloudiness
If it is not completely clear = the sample does not meet the criteria for work.
4. Removing it from the refrigerator “for an hour or two”
Short exposures add up and jeopardise stability.
Research status: All Peptology products are intended exclusively for laboratory use and research. They are not pharmaceutical products, have not been approved for human or veterinary use and do not replace medical advice. The protocol described is standard laboratory practice for working with lyophilised peptides.
How is it stored?
Lyophilised at room temperature, away from light. After reconstitution: with Peptide Matrix Water™ — up to 60 days at 2–8 °C; with bacteriostatic water — up to 28 days.
Purity and certificate of analysis
99%+ purity, HPLC/MS certificate for every batch.
SLU-PP-332 - 5mg - Batch - 0226 - Purity
Shipping and payment
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
🚚 Delivery information
- Orders placed by 15:00 are dispatched the same day, delivery in 5–7 working days.
-
Shipping with BOX NOW, chosen at checkout. Free shipping from €50, otherwise €2.
Frequently asked questions about SLU-PP-332
Where can I buy SLU-PP-332 in Cyprus and what does it cost?
In Cyprus you can buy SLU-PP-332 online from Peptology, from €75.00. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
What is SLU-PP-332?
SLU-PP-332 is synthetic ERRα/β/γ agonist. Peptology supplies it strictly for laboratory research.
In what form is SLU-PP-332 available?
As a lyophilised powder in a glass vial (5 mg). It is reconstituted in the laboratory with Peptide Matrix Water™ or bacteriostatic water; you can work out the concentration (mg/mL) with the <a href="/page/peptide-calculator">reconstitution calculator</a>.
Which side effects have been reported in clinical studies of SLU-PP-332?
As a newer research molecule, the safety profile of SLU-PP-332 in humans has not been characterised ; the data come exclusively from preclinical studies. Particular caution is required.
How long does delivery take and how do I pay?
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.