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GHK-Cu
GHK-Cu 100 mg – copper complex of the tripeptide Gly-His-Lys
Peptology Ltd. · Peptides for skin, sleep and libido
GHK-Cu is a copper complex of the tripeptide Gly-His-Lys that Peptology supplies strictly for laboratory research, in 100 mg. You can buy GHK-Cu in Cyprus online from €40.00, with same-day dispatch for orders placed by 15:00. 99%+ purity, HPLC/MS certificate for every batch, so every vial comes with documented quality data. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker. The product is not intended for human or veterinary use.
40,00 € · In stock
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
Last updated: 23/07/2026
What is GHK-Cu?
GHK-Cu (copper peptide, glycyl-L-histidyl-L-lysine + copper) is a natural tripeptide (GHK) that forms a complex with a copper(II) ion. GHK occurs naturally in plasma and has a high affinity for copper; its levels decline with age, which has been linked to a reduced capacity for tissue regeneration.
It is one of the most studied regenerative and rejuvenating peptides, with a central role in the synthesis of collagen, elastin and glycosaminoglycans, in healing, in skin remodelling and in protection from oxidative stress.
It is studied in research for skin and tissue regeneration, anti-ageing action, wound healing, the health of hair follicles and anti-inflammatory/antioxidant action. It is the “rejuvenating” component of the GLOW70 and GLOW50 formulas. See the range in the all peptides category.
In the Peptology version, it is supplied as a lyophilised research-grade powder with purity > 99%, in a 100 mg format. It is intended exclusively for scientific, research and in vitro applications — it is not a medicine or a cosmetic.
Available format: 100 mg
100 MG
High content
A large amount per vial, for extended research protocols.
PURITY
> 99%
Validated per batch, for reliable and repeatable research results.
How GHK-Cu works — copper transport and remodelling
COPPER TRANSPORT
It delivers bioavailable copper to cells — a cofactor of enzymes critical for the synthesis and stabilisation of collagen/elastin.
EXTRACELLULAR MATRIX SYNTHESIS
It stimulates the production of collagen, elastin and glycosaminoglycans, strengthening the structure and elasticity of the tissue.
GENE REGULATION
In gene expression studies, GHK appears to “reset” thousands of genes towards a healthier, more youthful pattern.
Why copper is needed
The biological action of GHK is closely linked to its ability to bind and carry copper(II). Copper is an essential cofactor of enzymes such as lysyl oxidase (stabilisation of collagen/elastin) and antioxidant defence enzymes — which is why the GHK-Cu complex is more active than the free peptide.
Together with regenerative peptides such as BPC-157 and TB-500, GHK-Cu adds the component of skin/extracellular matrix remodelling — which is why they are combined in the GLOW formulas. The mechanisms come from preclinical studies.
Properties and pharmacology
- Structure: GHK tripeptide (Gly-His-Lys) complexed with copper(II)
- Origin: natural plasma peptide; declines with age
- Main role: copper transport, synthesis of collagen/elastin/glycosaminoglycans
- Studied actions: regeneration, healing, anti-ageing, antioxidant, hair
- Synergy: with BPC-157 / TB-500 (GLOW formulas)
- Status: research peptide, not approved in this form
GHK-Cu vs. BPC-157 vs. TB-500
Comparison of the three peptides that are combined in the GLOW regenerative formulas. Reference data.
| GHK-Cu | BPC-157 | TB-500 | |
|---|---|---|---|
| Structure | Tripeptide + copper | Peptide (15 aa) | Thymosin Beta-4 fragment |
| Main focus | Skin / ECM remodelling | Repair / angiogenesis | Cell migration |
| Characteristic | Collagen / anti-ageing | Systemic repair | Cell motility |
| In the GLOW formulas | Yes | Yes | Yes |
| Status | Research | Research (WADA-prohibited) | Research (WADA-prohibited) |
Sources: literature on GHK-Cu, copper peptides and regenerative peptides.
Research
Skin, collagen and anti-ageing
GHK-Cu is one of the most studied peptides in dermatological research: in studies it promotes the synthesis of collagen and elastin, improves skin firmness and density and reduces signs of photoageing.
Healing and gene expression
In preclinical models, GHK accelerates healing and, in gene expression analyses, appears to reset the profile of many genes towards a more youthful pattern — something that fuels interest in anti-ageing applications.
Data limitations
Although there is a rich in vitro and topical-dermal background, systemic use is less well characterised. This particular form is offered as a research product.
Note: Scientific reference based on preclinical/dermatological data. It does not constitute medical advice or a claim for the product.
In brief — scientific profile
- GHK tripeptide complexed with copper — natural, declines with age
- Carries bioavailable copper — a cofactor of critical enzymes
- Synthesis of collagen/elastin/GAGs — tissue structure and elasticity
- Anti-ageing & healing — “resets” genes towards a youthful pattern
- Component of the GLOW formulas — with BPC-157 and TB-500
- Research product — not approved in this form
Side effects and safety
GHK-Cu is generally considered well tolerated, particularly with topical use. The reactions reported are mostly mild and local.
Common
- Reactions/redness at the application site
- Transient itching
- Mild stinging (topical use)
Less common
- Transient headache
- Dizziness
- Skin dryness/irritation
Precautions
- Allergic reaction / hypersensitivity
- Caution in copper metabolism disorders (e.g. Wilson’s disease)
- Avoid excessive copper load
Because it carries copper, there is a theoretical precaution in copper metabolism disorders. Scientific reference, not instructions for use.
Related peptides
GLOW70
BPC-157 + GHK-Cu + TB-500
GLOW50
Regenerative peptide formula
BPC-157
Repair peptide
Peptide Matrix Water™
Recommended reconstitution solvent
See: All peptides · Blog
Research warning: GHK-Cu is offered exclusively for scientific, research and in vitro purposes. It is not intended for human/veterinary use, or for the diagnosis, treatment or prevention of any condition, and does not constitute medical advice.
Can it be combined with other peptides?
Yes, it is often combined with BPC-157 or TB-500 for a synergistic effect in tissue repair and rejuvenation.
Buy GHK-Cu in Cyprus – price
You can buy GHK-Cu in Cyprus online from Peptology. Prices by strength:
- GHK-Cu: €40.00
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
GHK-Cu 100 mg: which strength
GHK-Cu is available in: 100 mg.
Research protocols
Important: Reference information for research purposes — not a recommendation for use or medical advice.
In the research literature, GHK-Cu is studied in both topical (dermal) and systemic approaches:
- In dermatological research it is often studied in topical forms for skin remodelling
- In systemic protocols it is studied in cycles, with tissue regeneration markers
- It is often combined with BPC-157 / TB-500 (the rationale of the GLOW formulas)
Available ready-combined in GLOW70 / GLOW50. The schedules come from the literature and do not constitute a recommendation for individual use.
Storage and reconstitution
It is supplied as a lyophilised powder in a 100 mg vial (a characteristic blue colour because of the copper). Lyophilised, it is stable at room temperature, away from light/humidity. For reconstitution, the recommended solvent is Peptide Matrix Water™, which significantly extends the shelf life of the solution.
- Before reconstitution: room temperature, away from light/moisture; up to 24 months.
- With Peptide Matrix Water™ (recommended): refrigerator 2–8 °C up to 60 days — the best stability option.
- With bacteriostatic water or sterile water: refrigerator 2–8 °C up to 28 days. No re-freezing.
- Reconstitution: add the solvent slowly down the wall of the vial, without vigorous agitation; the blue colour is normal.
Laboratory tip: Add Peptide Matrix Water™ to your basket — the recommended stabilising solvent for all reconstituted peptides.
Laboratory protocol — reconstitution, research protocols, storage
Standard protocol, applicable to all research peptides in the Peptology catalogue. For the concentration of the solution (mg/mL) per vial, use the peptide reconstitution calculator.
The 60-second protocol
1. SOLVENT
2. RECONSTITUTION
The solvent is added to the wall of the vial, without agitation, then wait 10–15 minutes.
3. CALCULATION
Calculator → concentration in mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilised powder |
| Solvent | Peptide Matrix Water |
| Volume for reconstitution | 1–3 mL — 3 mL maximum (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration is not mandatory) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you will need
Precision pipette
Calibrated, 100–1000 µL — for accurate measurement of the volume of solvent added to the vial.
70% alcohol pads
Two pads — to disinfect the peptide vial and the solvent vial.
Stabilised solvent for lyophilised peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Wrong |
|---|---|
| Disinfect the stoppers and the work surface with 70% alcohol, work with gloves | Working without disinfection |
| The solvent is added slowly down the wall of the vial | Direct jet onto the powder — foaming and denaturation |
| Light swirling between the palms | Shaking — foam, on which the peptides denature |
| Wait 10–15 minutes at room temperature | Mechanical mixing or heating |
| Visual inspection: clear, without particles | Using a cloudy or coloured solution |
Calculating the concentration
⚠️ Maximum 3 mL of solvent. The standard vial does not allow a larger volume — do not exceed it during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after addition (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 100 mg | 100 mg/mL | 50 mg/mL | 33.33 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in the original packaging. Refrigeration is not mandatory.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard the remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade the structure of the peptide.
Four mistakes to avoid
1. Shaking for “faster dissolution”
Foam = denaturation. Only gentle swirling between the palms.
2. Unsuitable solvent
For the stability of the peptide structure, use only a sterile, purpose-designed solvent — Peptide Matrix Water is recommended.
3. Ignoring slight cloudiness
If it is not completely clear = the sample does not meet the criteria for work.
4. Removing it from the refrigerator “for an hour or two”
Short exposures add up and jeopardise stability.
Research status: All Peptology products are intended exclusively for laboratory use and research. They are not pharmaceutical products, have not been approved for human or veterinary use and do not replace medical advice. The protocol described is standard laboratory practice for working with lyophilised peptides.
How is it stored?
The lyophilised vial is stored at room temperature, away from light. After reconstitution: with Peptide Matrix Water™ — up to 60 days at 2–8 °C; with bacteriostatic water — up to 28 days.
Purity and certificate of analysis
99%+ purity, HPLC/MS certificate for every batch.
GHK-Cu - 100 mg - Batch - 0226 - Purity
Shipping and payment
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
🚚 Delivery information
- Orders placed by 15:00 are dispatched the same day, delivery in 5–7 working days.
-
Shipping with BOX NOW, chosen at checkout. Free shipping from €50, otherwise €2.
Frequently asked questions about GHK-Cu
Where can I buy GHK-Cu in Cyprus and what does it cost?
In Cyprus you can buy GHK-Cu online from Peptology, from €40.00. Delivery in 5–7 working days with BOX NOW, free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.
What is GHK-Cu?
It is a natural tripeptide (GHK) complexed with copper(II). It carries bioavailable copper and stimulates the synthesis of collagen, elastin and glycosaminoglycans — the basis of its regenerative and anti-ageing properties.
In what form is GHK-Cu available?
As a lyophilised powder in a glass vial (100 mg). It is reconstituted in the laboratory with Peptide Matrix Water™ or bacteriostatic water; you can work out the concentration (mg/mL) with the <a href="/page/peptide-calculator">reconstitution calculator</a>.
Which side effects have been reported in clinical studies of GHK-Cu?
GHK-Cu is generally considered well tolerated, particularly with topical use. The reactions reported are mostly mild and local.
How long does delivery take and how do I pay?
Orders placed by 15:00 on working days ship the same day and are delivered in 5–7 working days with BOX NOW. Shipping costs €2 and is free from €50; you pay on delivery – by card through the BOX NOW payment link, before you open the locker.